Our mission
The lab develops and applies computational tools to study DNA and RNA aberrations that drive cancer and how these produce novel therapeutic opportunities.
We use bioinformatics and machine learning to characterize alterations in cancer cells and advance precision medicine for patients. Our methods can be applied to any tumor type, but we have special interest in cancers arising from immune cells and specifically chronic lymphocytic leukemia (CLL), a common B-cell leukemia.
Research projects
RNA aberrations in leukemia
Finding leukemia drivers that lay beyond DNA mutations
Novel neoantigen detection
Enabling precision immunotherapy by uncovering new sources of neoantigens
Immuno-
genomics of leukemia
Revealing the
bioclinical impact of leukemia-immune relations
RNA-seq analysis for Clinical Genomics of rare diseases
Solving unexplained
inherited disorders
Network analysis of single-cell RNA-seq
in aging and cancer
Understanding
RNA dysregulation
underlying age-related disease
We are actively recruiting highly motivated PhD students and Postdocs. MD students and programmers that are enthusiastic about cancer genomics and precision medicine are also welcome to apply.